abstract：BACKGROUND:Models of infectious disease are increasingly utilising empirical contact data to quantify the number of potentially infectious contacts between age groups. While a growing body of data is being collected on contact patterns across many populations, less attention has been paid to the social contacts of youn...

journal_title：BMC infectious diseases

authors： Campbell PT,McVernon J,Shrestha N,Nathan PM,Geard N

更新日期：2017-09-20 00:00:00

abstract：BACKGROUND:Local understandings of malaria and use of preventive measures-are critical factors in sustained control of malaria. This study assessed caretakers' knowledge on malaria, use of Long Lasting Insecticide Treated Nets (LLINs) and care-seeking behavior for their children's illness in different malaria transmiss...

journal_title：BMC infectious diseases

authors： Birhanu Z,Yihdego YY,Yewhalaw D

更新日期：2017-09-18 00:00:00

abstract：BACKGROUND:The clinical care of people living with HIV changed fundamentally as a result of the development of effective antiretroviral therapy (ART). HIV infection is now a long-term treatable condition. We report a national audit to assess adherence to British HIV Association guidelines for the routine investigation ...

journal_title：BMC infectious diseases

authors： Molloy A,Curtis H,Burns F,Freedman A,BHIVA Audit and Standards Sub-Committee.

更新日期：2017-09-13 00:00:00

abstract：BACKGROUND:Herpes simplex virus type 2 (HSV-2), one the most common causes of genital ulcers, appears to increase both the risk of HIV acquisition and HIV transmission. HSV-2/HIV co-infection among pregnant women may increase the risk of perinatal transmission of HIV. This study describes rates of HSV-2 among pregnant ...

journal_title：BMC infectious diseases

authors： Domercant JW,Jean Louis F,Hulland E,Griswold M,Andre-Alboth J,Ye T,Marston BJ

更新日期：2017-08-18 00:00:00

abstract：BACKGROUND:The existence of a bi-directional relationship between tuberculosis (TB) and insulin resistance (IR)/diabetes has been alluded to in literature. Although diabetes has been linked to increased tuberculosis risk, the relationship between tuberculosis as a causative factor for IR remains unclear. The study aime...

journal_title：BMC infectious diseases

authors： Philips L,Visser J,Nel D,Blaauw R

更新日期：2017-08-15 00:00:00

abstract：BACKGROUND:Hepatitis A virus (HAV) is a food and water-borne virus causing clinical (mainly hepatitis) and subclinical disease in humans. It is important to characterize circulating strains of HAV in order to prevent HAV infections using efficacious vaccines. The aim of this study was the detection and characterization...

journal_title：BMC infectious diseases

authors： Yilmaz H,Karakullukcu A,Turan N,Cizmecigil UY,Yilmaz A,Ozkul AA,Aydin O,Gunduz A,Mete M,Zeyrek FY,Kirazoglu TT,Richt JA,Kocazeybek B

更新日期：2017-08-11 00:00:00

abstract：BACKGROUND:Pentraxin-3 (PTX-3) is an acute-phase protein involved in inflammatory and infectious processes. This study assesses its diagnostic and prognostic value in patients with sepsis or septic shock in a medical intensive care unit (ICU). METHODS:The study includes 213 ICU patients with clinical criteria of sepsi...

journal_title：BMC infectious diseases

authors： Hamed S,Behnes M,Pauly D,Lepiorz D,Barre M,Becher T,Lang S,Akin I,Borggrefe M,Bertsch T,Hoffmann U

更新日期：2017-08-09 00:00:00

abstract：BACKGROUND:Improved treatment options of HIV have resulted in regular physical activities of many HIV-infected patients. However, data on effects of sports in HIV-patients are scarce. METHODS:21 HIV-infected persons were monitored prospectively while preparing for a marathon run. Multiple parameters with regard to imm...

journal_title：BMC infectious diseases

authors： Schlabe S,Vogel M,Boesecke C,Schwarze-Zander C,Rockstroh JK,Körner C,Brixius K,Wasmuth JC

更新日期：2017-08-08 00:00:00

abstract：BACKGROUND:In vitro data suggests that suboptimal initial vancomycin exposure may select for heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) infections. However, no clinical studies have evaluated the relationship between initial vancomycin exposure and emergence of hVISA. This pilot study seeks to ...

journal_title：BMC infectious diseases

authors： Martirosov DM,Bidell MR,Pai MP,Scheetz MH,Rosenkranz SL,Faragon C,Malik M,Mendes RE,Jones RN,McNutt LA,Lodise TP

更新日期：2017-08-02 00:00:00

abstract：BACKGROUND:To predict the risk of infectious diseases originating in wildlife, it is important to identify habitats that allow the co-occurrence of pathogens and their hosts. Puumala hantavirus (PUUV) is a directly-transmitted RNA virus that causes hemorrhagic fever in humans, and is carried and transmitted by the bank...

journal_title：BMC infectious diseases

authors： Khalil H,Olsson G,Magnusson M,Evander M,Hörnfeldt B,Ecke F

更新日期：2017-07-26 00:00:00

abstract：BACKGROUND:Although live-attenuated varicella-zoster virus (VZV) vaccines have been proven to be safe and effective in preventing varicella and real-word evidence shows routine childhood immunization programs are effective in dramatically reducing varicella associated morbidity and mortality, varicella vaccine is not i...

journal_title：BMC infectious diseases

authors： Meszner Z,Molnar Z,Rampakakis E,Yang HK,Kuter BJ,Wolfson LJ

更新日期：2017-07-14 00:00:00

abstract：BACKGROUND:In China, there were few studies about the pathogens of acute viral encephalitis and meningitis in children in recent years. The aims of this study were to characterize the etiology and prognosis of acute viral encephalitis and meningitis in Chinese children. METHODS:This was a multicentre prospective study...

journal_title：BMC infectious diseases

authors： Ai J,Xie Z,Liu G,Chen Z,Yang Y,Li Y,Chen J,Zheng G,Shen K

更新日期：2017-07-14 00:00:00

abstract：BACKGROUND:Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between infants with B. pertussis infection alone and those with respiratory viral coinfections. We also a...

journal_title：BMC infectious diseases

authors： Frassanito A,Nenna R,Nicolai A,Pierangeli A,Tozzi AE,Stefanelli P,Carsetti R,Concato C,Schiavoni I,Midulla F,Pertussis study group.

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:Rilpivirine is safe and effective in HIV-naïve patients with low baseline HIV-RNA or in switch strategy. It offers the advantages of few drug-drug interactions and a favourable toxicity profile. We aimed to determine the reasons for prescribing the rilpivirine (RPV)/tenofovir disoproxil (TDF)/emtricitabine (...

journal_title：BMC infectious diseases

authors： Sculier D,Gayet-Ageron A,Battegay M,Cavassini M,Fehr J,Hirzel C,Schmid P,Bernasconi E,Calmy A,Swiss HIV Cohort Study.

更新日期：2017-07-06 00:00:00

abstract：BACKGROUND:On 18 August 2015, Kyegegwa District reported eight deaths during a measles outbreak to the Uganda Ministry of Health (MoH). We investigated this death cluster to verify the cause, identify risk factors, and inform public health interventions. METHODS:We defined a probable measles case as onset of fever and...

journal_title：BMC infectious diseases

authors： Mafigiri R,Nsubuga F,Ario AR

更新日期：2017-07-03 00:00:00

abstract：BACKGROUND:Neonatal bloodstream infection (BSI) is the most important cause of morbidity and mortality in the neonatal intensive care unit (NICU). Although most neonatal BSIs are primary bacteremia, some are associated with a focus of infection. This distinction is not well characterized. METHODS:All patients with neo...

journal_title：BMC infectious diseases

authors： Wu IH,Tsai MH,Lai MY,Hsu LF,Chiang MC,Lien R,Fu RH,Huang HR,Chu SM,Hsu JF

更新日期：2017-07-03 00:00:00

abstract：BACKGROUND:Acute hepatitis A is a fecal-oral transmitted disease related to inadequate sanitary conditions. In addition to its traditional classification, several outbreaks in the men who have sex with men (MSM) population have resulted in acute hepatitis A being recognized as a sexually transmitted disease. However, f...

journal_title：BMC infectious diseases

authors： Chen NY,Liu ZH,Shie SS,Chen TH,Wu TS

更新日期：2017-06-20 00:00:00

abstract：BACKGROUND:Staphylococcus aureus strains are now regarded as zoonotic agents. In pastoral settings where human-animal interaction is intimate, multi-drug resistant microorganisms have become an emerging zoonotic issue of public health concern. The study of S. aureus prevalence, antimicrobial resistance and clonal linea...

journal_title：BMC infectious diseases

authors： Asiimwe BB,Baldan R,Trovato A,Cirillo DM

更新日期：2017-06-13 00:00:00

abstract：BACKGROUND:This paper studies the effect of mosquito abundance and malaria incidence in the last 3 weeks, and their interaction, on the hazard of time to malaria in a previously studied cohort of children in Ethiopia. METHODS:We model the mosquito abundance and time to malaria data jointly in a Bayesian framework. RE...

journal_title：BMC infectious diseases

authors： Belay DB,Kifle YG,Goshu AT,Gran JM,Yewhalaw D,Duchateau L,Frigessi A

更新日期：2017-06-12 00:00:00

abstract：BACKGROUND:Due to the populations' susceptibility, DENV-4 introduction in 2010 led to the occurrence of explosive epidemics in the following years in Brazil. In 2011, DENV-4 was identified in Rio de Janeiro (RJ) and it was prevalent in 2012 and 2013. Here, we aimed to characterize clinical, epidemiological and laborato...

journal_title：BMC infectious diseases

authors： Heringer M,Souza TMA,Lima MDRQ,Nunes PCG,Faria NRDC,de Bruycker-Nogueira F,Chouin-Carneiro T,Nogueira RMR,Dos Santos FB

更新日期：2017-06-09 00:00:00

abstract：BACKGROUND:We evaluated the effectiveness of targeted antimicrobial prophylaxis in transrectal ultrasound guided prostate biopsy (TRUSP). METHODS:A prospective, non-randomized cohort study was conducted. Rectal swab cultures plated on non-selective blood agar and on selective MacConkey agar supplemented with ciproflox...

journal_title：BMC infectious diseases

authors： Zembower TR,Maxwell KM,Nadler RB,Cashy J,Scheetz MH,Qi C,Schaeffer AJ

更新日期：2017-06-07 00:00:00

abstract：BACKGROUND:Due to limited therapeutic options, the spread of extended-spectrum beta-lactamases (ESBLs) have become a major public health concern. We conducted a prospective, randomized, open-label comparison of the therapeutic efficacy of piperacillin-tazobactam (PTZ), cefepime, and ertapenem in febrile nosocomial urin...

journal_title：BMC infectious diseases

authors： Seo YB,Lee J,Kim YK,Lee SS,Lee JA,Kim HY,Uh Y,Kim HS,Song W

更新日期：2017-06-07 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDTs) are alternative methods for microscopy in the diagnosis of malaria in resource limited settings. Among commercially available RDTs, CareStart™ Malaria test was found to show reliable results. This study evaluated the performance of CareStart™ Malaria Combo test kit in Northweste...

journal_title：BMC infectious diseases

authors： Feleke DG,Tarko S,Hadush H

更新日期：2017-06-06 00:00:00

abstract：BACKGROUND:A rare phenotype of clinical non-progressors to AIDS is not well understood and the new protocol for universal treatment, may block the understanding of viral control thus it is crucial to define this controversial group. METHODS:A cohort of 30 persons followed a criteria for viremia control groups 1 (VC1; ...

journal_title：BMC infectious diseases

authors： Gomes STM,Gomes ÉR,Dos Santos MB,Lima SS,Queiroz MAF,Machado LFA,Cayres-Vallinoto IMV,Vallinoto ACR,de O Guimarães Ishak M,Ishak R

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The clonal spread of multiple drug-resistant Acinetobacter baumannii is an emerging problem in China. We analysed the molecular epidemiology of Acinetobacter baumanni isolates at three teaching hospitals and investigated the risk factors, clinical features, and outcomes of hospital-acquired pneumonia caused ...

journal_title：BMC infectious diseases

authors： Li YJ,Pan CZ,Fang CQ,Zhao ZX,Chen HL,Guo PH,Zhao ZW

更新日期：2017-05-30 00:00:00

abstract：BACKGROUND:Corynebacterium striatum is a member of the non-diphtherial corynebacteria, which are ubiquitous in nature and generally colonize the skin and mucous membranes of humans. Rarely, it causes infective endocarditis (IE). We report a case of rare left atrial bacterial vegetative mass due to C. striatum masquerad...

journal_title：BMC infectious diseases

authors： Xu J,Yang Q,Li J,Zheng X

更新日期：2017-05-26 00:00:00

abstract：BACKGROUND:Intestinal parasitic infections are still one of the major health concerns in developing countries. Monitoring of intestinal parasitic infection and associated risk factors are essential for intervention strategies. Therefore, the aim of this study was to assess the prevalence of intestinal parasitic infecti...

journal_title：BMC infectious diseases

authors： Hailegebriel T

更新日期：2017-05-23 00:00:00

abstract：BACKGROUND:Klebsiella pneumoniae is a frequent nosocomial pathogen causing difficult-to-treat infections worldwide. The prevalence of Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae (KPC-KP) is increasing in China. The aim of this study was to investigate the molecular epidemiology of KPC-KP i...

journal_title：BMC infectious diseases

authors： Liang Y,Yin X,Zeng L,Chen S

更新日期：2017-05-23 00:00:00

abstract：BACKGROUND:Varicella is generally considered a mild disease. Disease burden is not well known and country-level estimation is challenging. As varicella disease is not notifiable, notification criteria and rates vary between countries. In general, existing surveillance systems do not capture cases that do not seek medic...

journal_title：BMC infectious diseases

authors： Riera-Montes M,Bollaerts K,Heininger U,Hens N,Gabutti G,Gil A,Nozad B,Mirinaviciute G,Flem E,Souverain A,Verstraeten T,Hartwig S

更新日期：2017-05-18 00:00:00

abstract：BACKGROUND:Kynurenine/Tryptophan ratio (KTR) is increased in HIV infection, and linked to immune activation. We hypothesized that early cART initiation results in lower KTR compared to late initiation. Furthermore, we hypothesized that KTR prior to cART is a predictor of the magnitude of subsequent reduction in immune ...

journal_title：BMC infectious diseases

authors： Gelpi M,Hartling HJ,Ueland PM,Ullum H,Trøseid M,Nielsen SD

更新日期：2017-05-16 00:00:00

abstract：BACKGROUND:Accurate influenza activity forecasting helps public health officials prepare and allocate resources for unusual influenza activity. Traditional flu surveillance systems, such as the Centers for Disease Control and Prevention's (CDC) influenza-like illnesses reports, lag behind real-time by one to 2 weeks, w...

journal_title：BMC infectious diseases

authors： Yang S,Santillana M,Brownstein JS,Gray J,Richardson S,Kou SC

更新日期：2017-05-08 00:00:00

abstract：BACKGROUND:The etiology of myxomatous mitral valve degeneration (MVD) is not fully understood and may depend on time or environmental factors for which the interaction of infectious agents has not been documented. The purpose of the study is to analyze the effect of Mycoplasma pneumoniae (Mp), Chlamydophila pneumoniae ...

journal_title：BMC infectious diseases

authors： Tiveron MG,Pomerantzeff PMA,de Lourdes Higuchi M,Reis MM,de Jesus Pereira J,Kawakami JT,Ikegami RN,de Almeida Brandao CM,Jatene FB

更新日期：2017-04-21 00:00:00

abstract：BACKGROUNDS:There are few studies focus on the factors underlying the late initiation of ART in China. We analyzed the trends in the median CD4 cell counts among different patient groups over time and the risk factors for the late initiation of ART in Shanghai, China. METHODS:A retrospective cross-sectional survey was...

journal_title：BMC infectious diseases

authors： Sun J,Liu L,Shen J,Chen P,Lu H

更新日期：2017-04-19 00:00:00

abstract：BACKGROUND:HIV is increasingly considered a chronic illness. More individuals are living longer and aging with the health-related consequences associated with HIV and multi-morbidity. Exercise is a self-management approach that can promote health for people aging with HIV. We examined the safety and effectiveness of pr...

journal_title：BMC infectious diseases

authors： O'Brien KK,Tynan AM,Nixon SA,Glazier RH

更新日期：2017-04-12 00:00:00

abstract：BACKGROUND:Screening household contacts of active tuberculosis (TB) patients is recommended for TB control. Due to resource constraints this rarely occurs in lower income countries. Demographic and clinical features of index cases may influence the likelihood of onwards TB transmission. It has also been proposed that a...

journal_title：BMC infectious diseases

authors： Hector J,Anderson ST,Banda G,Kamdolozi M,Jefferys LF,Shani D,Garton NJ,Mwale A,Jobe A,Davies GR,Sloan DJ

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:In chronic hepatitis C, the fibrosis progression rates are extremely variable and can be influenced by factors associated with the host, virus and environment. Among the associated metabolic factors, hepatic steatosis is characterized by an accumulation of triglycerides in hepatocytes. In the host, genetic d...

journal_title：BMC infectious diseases

authors： Magri MC,Prata TV,Manchiero C,Dantas BP,Mazza CC,Tengan FM

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:Culturing has long been the gold standard for detecting aetiologic agents in bacterial infections. In some cases, however, culturing fails to detect the infection. To further investigate culture-negative samples, amplification and subsequent sequencing of the 16S rRNA gene is often applied. The aim of the pr...

journal_title：BMC infectious diseases

authors： Stavnsbjerg C,Frimodt-Møller N,Moser C,Bjarnsholt T

更新日期：2017-03-27 00:00:00

abstract：BACKGROUND:Levels of non-neutralising antibodies (AB) to the C5 domain of HIV Env gp120 are inversely related to progression of HIV infection. In this phase I/II clinical study we investigated safety of Vacc-C5, a peptide-based therapeutic vaccine candidate corresponding to C5/gp41732-744 as well as the effects on pre-...

journal_title：BMC infectious diseases

authors： Brekke K,Sommerfelt M,Ökvist M,Dyrhol-Riise AM,Kvale D

更新日期：2017-03-24 00:00:00

abstract：BACKGROUND:Herpes simplex virus (HSV) is a common human pathogen that causes a variety of diseases, including oral-labial, genital lesions and life-threatening encephalitis. The antiviral nucleoside analogues such as acyclovir are currently used in anti-HSV therapies; however, clinical overuse of these drugs has led to...

journal_title：BMC infectious diseases

authors： Hou J,Zhang Z,Huang Q,Yan J,Zhang X,Yu X,Tan G,Zheng C,Xu F,He S

更新日期：2017-03-20 00:00:00

abstract：BACKGROUND:The real burden of smear-positive (PTB+) and bacteriologically confirmed tuberculosis (BCTB) in Ethiopia is not known. Thus, the aim of this community-based study was to measure the prevalence and incidence of tuberculosis in the Hetosa District of Oromia Region, Ethiopia. METHODS:First, a population-based ...

journal_title：BMC infectious diseases

authors： Hamusse S,Demissie M,Teshome D,Hassen MS,Lindtjørn B

更新日期：2017-03-16 00:00:00